If you have wrist/elbow pain, or carpal tunnel syndrome, you can try using handheld mouse. Handheld mouse,no need plane support, no operating space restriction, this definitely allow you change to a natural, pain-free of posture and encourages the movement of shoulder and whole body instead of just the hand or the wrist.
Handheld mouse is effective to prevent Repetitive Strain Injury (RSI) and Carpal Tunnel Syndrome which caused due to long-term continuous and repetitive finger, hand or arm movements or improper posture while handling mouse.